Synonyme(s) : Isonicotinamide ; Pyridine-4-carboxylic acid amide ; nicotinamide impurity D.

Application
Isonicotinamide (pyridine-4-carboxamide) can be used as a heterocyclic building block to synthesize:

 - 4-oxo-1,3-thiazinan-3-yl isonicotinamide derivatives as potential anti-tubercular agents.
 - Organotin(IV) complexes of isonicotinamide via synthesis of phosphoramidate ligands for various biological activity studies.
 - Bis-pyridinium isonicotinamide derivatives of 2-(hydroxyimino)-N-(pyridin-3-yl)acetamide as potent reactivators sarin.

It can also be used as a co-former with active pharmaceutical ingredients (APIs) to prepare co-crystals.