Synonyme(s): SU 11248, SU 011248, SU112248, N-[2-(Diethylamino)ethyl]-5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide (2S)-2-hydroxybutanedioic acid (1:1) salt.

Sunitinib malate has been used:
    to study its mechanism in the inhibition of MCF-7 cell migration and angiogenesis
    as a reference molecule to compare its docking energies with other ligands/vascular endothelial growth factor receptor (VEGF) receptor blocker
    used in proliferation assay

Actions biochimiques/physiologiques
Sunitinib has greater bioavailability and potency compared to other inhibitors. It prevents angiogenesis.
Sunitinib malate is a receptor tyrosine kinase inhibitor, which targets VEGF-R1, VEGF-R2, VEGF-R3, PDGF-Rα, PDGF-Rβ, KIT, FLT3, CSF-1R, and RET. Sunitinib malate is an anticancer drug.

Poids	0,54 Kg   (540 g)
Volume	0,0056 m³   (5600 cm³)
Largeur	0,15 m   (15 cm)
Longueur	0,15 m   (15 cm)
Hauteur	0,25 m   (25 cm)

Les dimensions, le poids et le volume sont bruts (emballage inclus)